Gaining confidence in local anaesthesia

Gaining Confidence in Goal-based Safety Cases

Goal-based safety standards are now a reality. As well as confidently satisfying the mandatory requirements laid down in these standards, there are a number of other secondary factors that influence the confidence a regulator or assessor has in any safety case produced. These factors include novelty of argument approach, experience of stakeholders and scale of the system and safety case. Curren...

Gaining confidence in high-throughput screening.

T he search for novel organic molecules with biological activity on human, animal, and plant physiological systems has passed through many phases over the centuries. From first steps testing single molecules on whole living systems to fully automated high-throughput screening (HTS) testing tens or hundreds of thousands of molecules per day on purified protein targets, the search has become ever...

Caesarean in mare by Marcenac incision under local anaesthesia

A nulliparous non-descript mare was presented with a complaint of dystocia. The mare was recumbent and physical examination revealed that the animal was in shock. There was no straining and foetal forelimbs were visible outside the vulva. The foetus was dead as there was no pedal reflex. Vaginal examination revealed anterior presentation with dorso-sacral position and rigid lateral head deviati...

Gaining Confidence in Scientific Applications Through Executable Interface Contracts

Interface contract enforcement is intended to help scientists gain confidence in software built from third-party components. Unfamiliar components present increased risk of incorrect or unanticipated usage patterns and unexpected component behavior. Executable interface contracts can address these issues but may incur unacceptable overhead. Research into techniques for performance-driven contra...

Choice in local anaesthesia.